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Metabolic processes in the body and environmental factors, including oxidation, hydrolysis, deamination, UV irradiation, radiation, and special chemical substances can cause DNA damage. The damage repair mechanism inherent in the body can repair most of the DNA damage, but the DNA damage caused by extraction during the research process will remain on the DNA. If it is not repaired, it will affect the subsequent experiment. VAHTS DNA Damage Repair Kit can be used to repair most DNA damage. The kit contains a variety of enzymes for DNA damage repairing and specially optimized buffer, suitable for a variety of DNA damages, such as apurine/apyrimidine sites, thymine dimers, de-aminocytosine, 8-oxoguanine, oxidized bases, nicks and gaps, deamination cytosine, 3' terminal half group blocking, etc. This kit can be used to repair formalin fixed paraffin embedding (FFPE) DNA damage and DNA damage caused by various environments or processing methods. But it cannot be used to repair all kinds of DNA damages, such as double-strand breaks and DNA-protein crosslink. This kit can effectively improve the quality of DNA. It has a wide range of compatibility, and the products can be directly used in PCR and second-generation sequencing library construction, third-generation sequencing library construction, etc.
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