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DNase I , RNase-free EN401-402

DNase I , RNase-free EN401-402

SKU: #001 - In Stock

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Product Detail

Application Notes

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Product Introduction

Deoxyribonuclease I (DNase I) is an endonuclease that digests single- or double-stranded DNA. It recognizes and cleaves phosphodiester bonds to produce a single deoxynucleotide or single- or double-stranded oligodeoxynucleotide with 5'-phosphorylated and 3'-hydroxylated ends. The activity of DNase I depends on Ca2+, and DNase I can also be activated by divalent metal ions such as Mg2+ and Mn2+. In the presence of Mg2+, DNase I nonspecifically recognizes and cleaves a double-stranded DNA at any site on either strand, and in the presence of Mn2+, it recognizes and cleaves almost the same sites on both strands of the DNA to produce DNA fragments with blunt ends or sticky ends with one or two nucleotide overhangs.

Product Advantages

High activity
Very low RNase residue
Good stability




Store at -30 ~ -15℃ for up to 24 months. Transportation conditions: ≤0℃.

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