High-throughput automation is reshaping molecular breeding—delivering unprecedented speed, consistency, and scalability across sample preparation workflows. At the heart of Vazyme’s solution are two core instruments:

• The VNP-96P Automated Nucleic Acid Extraction Instrument, paired with optimized reagent kits, efficiently purifies nucleic acids from up to 96 biological samples in a single run.

• The VNL-96P Automated Liquid Handling Workstation enables long-term unattended operation with exceptional accuracy, throughput, and compati-bility—offering a user-friendly and cost-effective solution for complex liquid handling tasks.

Together, these platforms establish a fully automated and scalable sample preparation pipeline, delivering key advantages in molecular breeding:

• Efficiency Boost

Tasks that once required multiple technicians over several days can now be completed by a single operator in just four hours—maximizing output while minimizing human input.

• Shortened Breeding Cycles

Faster sample preparation translates directly into reduced turnaround time, helping breeders accelerate decision-making and overall project timelines.

• Cost Optimization

By lowering labor demands and optimizing reagent usage, researchers can redirect resources toward higher-value scientific work—enhancing both productivity and budget efficiency.

In a field where both speed and cost control are critical, high-throughput automation offers a decisive advantage. With Vazyme’s fully integrated plat-forms, molecular breeding operations become more streamlined, scalable, and scientifically advanced.

Cost control is a constant challenge in molecular breeding—and high-throughput automation offers a practical and scalable solution. By combining automated nucleic acid extraction with streamlined library preparation systems, researchers can process large volumes of samples efficiently and consistently, dramatically reducing the cost per sample.

With their strong advantages in speed, accuracy, and resource optimization, automated extraction instruments and liquid handling platforms are not only lowering barriers to entry but also paving the way for a more standardized and data-driven approach to modern breeding.

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Breakthroughs in ultra-fast amplification technologies are reshaping molecular breeding timelines. By drastically reducing the time needed for gene amplification and detection, these innovations help streamline experiments and accelerate breeding workflows.

Vazyme's next-generation hot-start Taq DNA polymerase, built with dual-species high-affinity antibodies and an optimized buffer system, achieves amplification speeds of just 1–15 sec/kb —without compromising specificity or success rate.

This powerful performance provides reliable support for time-sensitive applications such as genotyping, enabling faster, more precise decision-making across breeding programs.

• Ultra-Fast PCR, 75% Time Saved

Rapid amplification technologies have introduced significant time savings across key steps in molecular breeding.

PCR workflows, which traditionally required 2–3 hours using standard Taq polymerases, can now be completed in just 30 minutes with ultra-fast reagents—cutting amplification time by as much as 75%.

• High-Speed Genotyping, High-Impact Results

In genotyping applications, the integration of high-throughput sequencing platforms and accelerated data analysis pipelines has shortened turnaround times from days or even weeks to just a few hours, enabling faster, more efficient detection

• Accelerate the Entire Breeding Timeline

These advances also contribute to significantly shorter experimental cycles overall. Breeding workflows that once took several months can now be completed in a matter of weeks, supporting quicker germplasm screening and the accelerated development of elite lines.

Ultra-fast amplification and rapid-result technologies work in synergy to revolutionize molecular breeding timelines. By enabling high-yield target amplification within minutes, ultra-fast PCR not only cuts reaction time dramatically but also reduces the overall cost of instrumentation, labor, and reagents. At the same time, rapid-result systems streamline multiple steps from amplification to detection, accelerating workflows end to end. Together, these advancements unlock faster decisions, higher throughput, and smarter breeding outcomes.

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Innovations in high-fidelity gene editing and molecular marker validation have redefined the standards of precision in modern breeding. By minimizing mutation rates and eliminating redundant experiments, these technologies accelerate results while improving reliability.

At the forefront of this shift is Phanta UniFi, Vazyme's next-generation high-fidelity DNA polymerase, engineered through the BioSmart platform for unmatched accuracy and versatility. Offering an ultra-high fidelity up to 220× higher than conventional Taq and broad Tm adaptability, Phanta UniFi delivers exceptional results in demanding applications such as molecular cloning, sequencing, and site-directed mutagenesis. Its consistent, high-precision performance empowers scientists to confidently push forward complex breeding strategies with reduced errors and maximum efficiency.

• Lower Risk of Off-Target Mutations

Advanced gene editing technologies and robust molecular marker validation significantly reduce the risk of off-target mutations, eliminating many potential downstream errors early in the breeding pipeline. This precision provides greater confidence in experimental outcomes and accelerates the path to reliable trait selection.

• Fewer Repetitions, Greater Efficiency

Traditional workflows often suffer from low editing precision and marker instability, requiring multiple verification rounds that consume valuable time and resources. In contrast, upgraded high-fidelity systems ensure consistently accurate results, cutting repeated experiments by more than 50%—allowing breeding teams to focus on progress rather than correction.

In molecular breeding, ultra-high-fidelity amplification technologies serve as a cornerstone of precision and reliability. By minimizing errors during target fragment amplification, they ensure superior accuracy of PCR results and drastically reduce the need for repeated experiments. This not only conserves valuable resources—including instrumentation, reagents, and labor—but also increases overall operational efficiency.

Meanwhile, next-generation high-fidelity gene editing and marker validation platforms continue to drive performance gains. Their ability to lower mutation rates and improve reproducibility contributes to significantly shorter breeding timelines, laying a robust foundation for faster, more predictable breeding programs.

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KASP (Kompetitive Allele Specific PCR) introduces a powerful and cost-effective approach to genotyping in molecular breeding. By leveraging competitive allele-specific PCR, it enables accurate bi-allelic detection of SNPs and InDels within complex genomic backgrounds—making it an ideal tool for fine mapping of trait-associated genes and marker-assisted selection (MAS).

Vazyme's CAUP Genotyping U+ Probe Master Mix, pre-loaded with universal fluorescent probes, simplifies the process by requiring only custom primers tailored to specific targets. This streamlined workflow not only minimizes experimental setup time and costs but also enhances locus detection accuracy, accelerating breakthroughs in high-efficiency molecular breeding.

• High Throughput, Streamlined Screening

KASP enables the simultaneous detection of multiple SNP loci within a single experiment, making it ideal for high-throughput genotyping across large breeding populations. This capability supports the rapid identification of elite genotypes, helping breeders accelerate selection timelines and improve efficiency.

• High Accuracy, Reliable Insights

Powered by the precision of allele-specific PCR, KASP delivers accurate genotyping of SNPs and InDels. Its consistency and reliability make it especially suitable for trait gene mapping and marker-assisted selection, where data integrity is critical.

• High Flexibility, Broad Applicability

With customizable primer design, KASP is highly adaptable across diverse species and breeding objectives. Whether applied to crops or livestock, early-stage research or advanced selection, its flexibility empowers a wide range of molecular breeding strategies.

Thanks to its outstanding advantages in throughput, accuracy, and flexibility, KASP has emerged as a cornerstone technology in modern molecular breeding. It facilitates rapid and precise genotyping across large-scale breeding populations, significantly enhancing the efficiency of selection and accelerating fine mapping of trait-associated genes.

Beyond just improving speed and accuracy, KASP contributes to accelerated crop improvement, promotes greater genetic diversity, and empowers precision breeding at scale. As breeding programs grow in complexity and ambition, KASP continues to provide robust technical support, driving molecular breeding forward with confidence.